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项目名称
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中文全称
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英文名
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CAS
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化学名
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依匹哌唑
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依匹哌唑
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Brexpiprazole
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913611-97-9
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7-[4-(4-苯并[b]噻吩-4-基-1-哌嗪)丁氧基]-2(1h)-喹啉酮
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依匹哌唑中间体1
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7-(4-chlorobutoxy)-1H-quinolin-2-one
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913613-82-8
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7-(4-氯丁氧基)-3,4-二氢-2(1H)-喹啉酮
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依匹哌唑中间体2
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1-(Benzo[b]thiophen-4-yl)piperazine
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846038-18-4
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1-(苯并[B]噻吩-4-基)哌嗪
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依匹哌唑 KSM1
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4-BROMO-BENZO[B]THIOPHENE
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5118-13-8
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4-溴苯并[B]噻吩
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依匹哌唑 KSM2
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7-Hydroxyquinolinone
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70500-72-0
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7-羟基-2-喹诺酮
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依匹哌唑 KSM3
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4-chloro- Benzo[b]thiophene
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66490-33-3
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4-氯苯并噻吩
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赛乐西帕
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赛乐西帕
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2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methylsulfonylacetamide
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475086-01-2
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赛乐西帕；2-{4-[(5,6-二苯基吡嗪-2-基)(异丙基)氨基]丁氧基}-N-(甲基磺酰基)乙酰胺
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赛乐西帕中间体1
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4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]-1-butanol
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475086-75-0
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[4-[(5,6-二苯基吡嗪基)(2-异丙基）氨基]-1-正丁醇
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赛乐西帕中间体2
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2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester
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475084-96-9
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2-{4-[N-(5,6-二苯基吡嗪基)-N_异丙基氨基]正丁氧基}乙酸叔丁醇酯
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赛乐西帕中间体3
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[4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID
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475085-57-5
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[4-[(5,6-二苯基吡嗪基)(1-甲基乙基)氨基]丁氧基]乙酸
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赛乐西帕KSM 1
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5-chloro-2,3-diphenylpyrazine
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41270-66-0
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5-氯-2,3-二苯基哌嗪5-氯-2,3-二苯基哌嗪
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赛乐西帕KSM 2
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4-(Isopropylamino)butanol
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42042-71-7
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4-(异丙基氨基)-1-丁醇
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赛乐西帕KSM 3
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5-Iodo-2,3-diphenylpyrazine
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101727-15-5
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5-碘-2,3-二苯基吡嗪
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氢溴酸沃替西汀
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氢溴酸沃替西汀
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Vortioxetine HBR
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960203-27-4
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1-[2-[(2,4-二甲基苯基)硫基]苯基]哌嗪氢溴酸盐
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沃替西汀
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Vortioxetine
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508233-74-7
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1-[2-(2,4-甲基苯硫基)苯基]哌嗪;1-(2-((2,4-二甲基苯基)硫代)苯基)哌嗪;4-[-2-(2,4-二甲基-苯硫烷基)-苯基-哌嗪
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沃替西汀HBR KSM 2
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(2,4-dimethylphenyl)(2-nitrophenyl)sulfane
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1610527-49-5
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2-(2,4-二甲基苯硫基 ) 硝基苯
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沃替西汀HBR KSM 3
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2-((2,4-dimethylphenyl)thio)aniline
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1019453-85-0
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2-((2,4-甲基苯基)硫代)苯胺
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沃替西汀HBR KSM 1
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1-[(2-BroMophenyl)thio]-2,4-diMethylbenzene
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60203-41-2
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1-[(2-溴苯基)硫基]-2,4-二甲基苯
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乙磺酸尼达尼布
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乙磺酸尼达尼布
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nintedanib esylate；(3S,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-cyclohexanecarboxylic Acid Methyl Ester
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656247-18-6
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(3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯乙磺酸盐
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乙磺酸尼达尼布
中间体1
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1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
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1160293-25-3
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1-(2-氯乙酰基)-2-氧代吲哚啉-6-羧酸甲酯
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乙磺酸尼达尼布
中间体2
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(E)-methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
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1174335-83-1
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(3E)-1-(2-氯乙酰基)-2,3-二氢-3-(甲氧基苯基亚甲基)-2-氧代-1H-吲哚-6-羧酸甲酯
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乙磺酸尼达尼布
中间体3
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(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylicacid methyl ester
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1168150-46-6
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2,3-二氢-3-(甲氧基苯基亚甲基)-2-氧代-1H-吲哚-6-羧酸甲酯
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乙磺酸尼达尼布
中间体4
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methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120)
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656247-17-5
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(3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯
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乙磺酸尼达尼布KSM1
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Methyl oxindole-6-carboxylate
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14192-26-8
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2-氧化吲哚-6-甲酸甲酯
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乙磺酸尼达尼布KSM2
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N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
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262368-30-9
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N-(4-氨基苯基)-N,4-二甲基-1-哌嗪乙酰胺
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沃拉帕沙
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沃拉帕沙
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Vorapaxar Sulfate
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705260-08-8
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沃拉帕沙硫酸盐
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沃拉帕沙中间体2
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4-nitroheptanedial
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147189-43-3
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4-硝基庚二醛
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沃拉帕沙中间体3
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5-nitrocyclohexene-1-carbaldehyde
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900186-75-6
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5-硝基-1-环己烯-1-羧醛
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沃拉帕沙中间体4
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(E)-3-(5-nitrocyclohexen-1-yl)prop-2-enoic acid
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899809-64-4
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(E)-3-(5-硝基-1-环己烯-1-基)丙烯酸
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沃拉帕沙中间体5
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N,N-diphenylimidazole-1-carboxamide
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2875-79-8
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N,N-二苯基-1H-咪唑甲酰胺
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沃拉帕沙中间体6
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(R)-4-hydroxy-N,N-diphenylpent-2-ynamide
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899809-61-1
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(4R)-4-羟基-N,N-二苯基-2-戊炔酰胺
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沃拉帕沙中间体7
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[(5-bromo-2-pyridinyl)methyl]-phosphonic acid diethyl ester;
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380893-73-2
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(5-溴吡啶-2-基)甲基磷酸二乙酯
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沃拉帕沙中间体8
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[[5-(3-fluorophenyl)-2-pyridinyl]Methyl]-, diethyl ester
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380894-77-9
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二乙基((5-(3-氟苯基)吡啶-2-基)甲基)磷酸酯
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沃拉帕沙中间体9
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(R)-5-(diphenylamino)-5-oxopent-3-yn-2-yl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate
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899809-60-0
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(2E)-3-(5-硝基-1-环己烯-1-基)-2-丙烯酸 (1R,2Z)-4-(二苯基氨基)-1-甲基-4-氧代-2-丁炔-1-基酯
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沃拉帕沙中间体10
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(R,E)-5-(diphenylamino)-5-oxopent-3-en-2-yl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate
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900186-73-4
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(2E)-3-(5-硝基-1-环己烯-1-基)-2-丙烯酸 (1R,2Z)-4-(二苯基氨基)-1-甲基-4-氧代-2-丁烯-1-基酯
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沃拉帕沙中间体11
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(3R,3aS,4S,4aS,7R,9aR)-1,3,3a,4,4a,5,6,7,8,9a-Decahydro-3-methyl-7-nitro-1-oxo-N,N-diphenylnaphtho[2,3-c]furan-4-carboxamide
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900186-72-3
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(3R,3aS,4S,4aS,7R,9aR)-1,3,3a,4,4a,5,6,7,8,9a-十氢-3-甲基-7-硝基-1-氧代-N,N-二苯基萘并[2,3-c]呋喃-4-甲酰胺
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沃拉帕沙中间体12
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[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(Diphenylamino)carbonyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic acid ethyl ester
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900161-12-8
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[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(二苯基氨基)羰基]十二氢-1-甲基-3-氧代萘并[2,3-c]呋喃-6-基]氨基甲酸乙酯
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盐酸阿考替胺
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盐酸阿考替胺
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Acotiamide Hydrochloride
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773092-05-0
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N -{2-[双（1-甲基乙基）氨基]乙基}-2-（[ 2-羟基-4,5-二甲氨基苄基）胺]噻唑-4-酰胺 单盐酸盐三水合物
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盐酸阿考替胺
中间体2
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ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate
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185105-98-0
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2-[N-(2,4,5-三甲氧基苯甲酰基)氨基]-4-乙氧基羰基-1,3-噻唑
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阿伐那非
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阿伐那非
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Avanafil
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330784-47-9
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4-[(3-氯-4-甲氧基苄基)氨基]-2-[2-(羟甲基)-1-吡咯烷基]-N-(2-嘧啶基甲基)-5-嘧啶甲磺酰胺
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阿伐那非
中间体2
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ethyl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
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330785-83-6
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（S）-4-（3-氯-4-甲氧基苄基氨基）-5-乙氧羰基-2-（2-羟甲基-1-吡咯烷基）嘧啶
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阿伐那非
中间体3
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(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
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330785-84-7
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（S）-4-（3-氯-4-甲氧基苄基氨基）-5-羧基-2-（2-羟甲基-1-吡咯烷基）嘧啶
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雷美替胺
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雷美替胺
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Ramelteon
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196597-26-9
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(S)-N-(2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-基)乙基)丙酰胺
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雷美替胺中间体1
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(E)-2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile
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196597-79-2
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E-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-亚基)乙腈
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雷美替胺中间体2
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2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine
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448964-37-2
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2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-基)乙胺
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雷美替胺中间体3
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(S)-2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-aminium chloride
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196597-80-5
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S-2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-基)乙胺盐酸盐
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Brigatinib
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Brigatinib
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AP26113 (Brigatinib)
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1197953-54-0
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5-氯-N2-[4-[4-(二甲基氨基)-1-哌啶基]-2-甲氧基苯基]-N4-[2-(二甲基亚膦酰)苯基]-2,4-嘧啶二胺
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AP26113中间体4
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[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine
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761440-75-9
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2-甲氧基-4-[4-(4-甲基-1-哌嗪基)-1-哌嗪基]-盐酸苯胺
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AP26113中间体1
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2,5-dichloro-N-(2-(diMethylphosphoryl)phenyl)pyriMidin-4-aMine
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1197953-49-3
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AP26113中间体1
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AP26113中间体
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2-(diMethylphosphoryl)aniline
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1197953-47-1
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2-(二甲基氧磷基)苯胺
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AP26113中间体3
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1-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-Methylpiperazine
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761440-65-7
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1-(1-(3-甲氧基-4-硝基苯基)哌啶-4-基)-4-甲基哌嗪
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阿可替尼
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acalabrutinib
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(S)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
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1420477-60-6
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ACP-196；苯甲酰胺, 4-[8-氨基-3-[(2S)-1-(1-氧代-2-丁炔-1-基)-2-吡咯烷基]咪唑并[1,5-A]吡嗪-1-基]-N-2-吡啶基-
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Acalabrutinib
中间体1；（ACAT-004）
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1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)-
|
1418307-17-1
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1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)-
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Acalabrutinib 中间体2（ACAT-005）
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(S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
|
1418307-18-2
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(S)-8-氯-3-(N-CBZ-2-四氢吡咯基)咪唑[1,5骈]吡嗪
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Acalabrutinib 中间体3（ACAT-007）
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1-Pyrrolidinecarboxylic acid, 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester, (2S)-
|
1420478-88-1
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(S)-苯基 2-(8-氨基-1-溴咪唑[1,5-a]吡嗪-3-基)吡咯烷-1-羧酸酯
|
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Acalabrutinib 中间体4（ACAT-008）
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4-(PYRIDIN-2-YL)AMINOCARBONYLPHENYLBORONIC ACID
|
850568-25-1
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4-(砒啶-2-基)甲酰氨苯基硼酸
|
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Acalabrutinib 中间体
|
(3-Chloropyrazin-2-yl)MethanaMine hydrochloride
|
939412-86-9
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(3-氯吡嗪-2-基)甲胺盐酸
|
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Abemaciclib
|
Abemaciclib base
|
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine
|
1231929-97-7
|
LY2835219；N-[5-[(4-乙基-1-哌嗪基)甲基]-2-吡啶基]-5-氟-4-[4-氟-2-甲基-1-异丙基-1H-苯并咪唑-6-基]-2-嘧啶胺
|
|
Abemaciclib Mesylate
|
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine
|
1231930-82-7
|
N-[5-[(4-乙基-1-哌嗪基)甲基]-2-吡啶基]-5-氟-4-[4-氟-2-甲基-1-异丙基-1H-苯并咪唑-6-基]-2-嘧啶胺甲烷磺酸盐
|
|
LY2835219中间体4
|
1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
|
1231930-37-2
|
1H-苯并咪唑, 4-氟-2-甲基-1-(异丙基)-6-(4,4,5,5-四甲基-1,3,2-二氧杂环己硼烷-2-基)-
|
|
LY2835219中间体（KSM-1）
|
1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-
|
1231930-42-9
|
6-(2-氯-5-氟-嘧啶-4-基)-4-氟-1-异丙基-2-甲基-1H-苯并咪唑
|
|
LY2835219中间体6
KSM-2
|
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
|
1180132-17-5
|
5-[(4-乙基哌嗪-1-基)甲基]吡啶-2-胺
|
|
LY2835219中间体7
|
6-Aminonicotinaldehyde
|
69879-22-7
|
2-氨基-5-醛基吡啶
|
|
LY2835219中间体1
|
N-Isopropylacetamide
|
1118-69-0
|
N-异丙基乙酰胺
|
|
ABEMACICLIB中间体
|
EthaniMidaMide, N-(4-broMo-2,6-difluorophenyl)-N'-(1-Methylethyl)-
|
1231930-29-2
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N-(4-溴-2,6-二氟-苯基)-N'-异丙基-乙酰胺
|
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LY2835219中间体3
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6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
|
1231930-33-8
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6-溴-4-氟-1-异丙基-2-甲基-1H-苯并[D]咪唑
|
|
LY2835219中间体5
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1-((6-bromopyridin-3-yl)methyl)-4-ethylpiperazine
|
1231930-25-8
|
1-[(6-溴-3-吡啶基)甲基]-4-乙基-哌嗪
|
|
咪达那新
|
咪达那新
|
Imidafenacin
|
170105-16-5
|
4-(2-甲基-1H-咪唑-1-基)-2,2-二苯基丁酰胺
|
|
咪达那新中间体1
|
4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile
|
214777-43-2
|
4-（2-甲基-1-咪唑基）-2,2-二苯基丁腈
|
|
咪达那新中间体2
|
4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile phosphenoperoxoic acid
|
893421-55-1
|
4-（2-甲基-1-咪唑基）-2,2-二苯基丁腈磷酸盐
|
|
咪达那新中间体3
|
4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride
|
893421-54-0
|
4-(2-甲基-1H-咪唑-1-基)-2,2-二苯基丁酰胺盐酸盐
|
|
阿齐沙坦
|
阿齐沙坦
|
Azilsartan
|
147403-03-0
|
2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-基)联苯-4-基]甲基]苯并咪唑-7-羧酸
|
|
阿齐沙坦
中间体1
|
ethyl (Z)-2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
|
1397836-41-7
|
1-[(2'-(羟基脒基)[1,1-联苯基]-4-基)甲基]-2-乙氧基-1H-苯并咪唑-7-羧酸乙酯
|
|
阿齐沙坦
中间体2
|
ethyl 2-ethoxy-1-((2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
|
1403474-70-3
|
2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-基)联苯-4-基]甲基]苯并咪唑-7-羧酸乙酯
|
|
盐酸考尼伐坦
|
盐酸考尼伐坦
|
Conivaptan hydrochloride
|
168626-94-6
|
[1,1' - 联苯] -2 - 甲酰胺，N-[4 - [（4,5 - 二氢-2 - 甲基咪唑并[4,5-d〕[4]苯并氮杂-6（1H） - 基）羰基]苯基] 盐酸盐
|
|
盐酸考尼伐坦
中间体2
|
4-([1,1'-biphenyl]-2-carboxamido)benzoic acid
|
168626-74-2
|
4-（联苯-2-酰胺基）苯甲酸
|
|
马西替坦
|
马西替坦
|
Macitentan
|
441798-33-0
|
N-[5-(4-溴苯基)-6-[2-[(5-溴-2-嘧啶基)氧]乙氧基]-4-嘧啶基]-N'-丙基磺酰胺
|
|
马西替坦
中间体1
|
N-(5-(4-bromophenyl)-6-chloropyrimidin-4-yl)propane-1-sulfamide
|
1393813-42-7
|
N-（5-（4-溴苯基）-6-氯嘧啶-4-丙基磺酰胺
|
|
马西替坦
中间体2
|
N-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide
|
1393813-43-8
|
N-（5-（4-溴苯基）-6-（2-嘧啶-4-丙基磺酰胺
|
|
维拉唑酮
|
盐酸维拉佐酮
|
Vilazodone
|
163521-12-8
|
盐酸维拉佐酮
|
|
中间体1
|
5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxylic acid ethyl ester hydrochlorid
|
1422956-25-9
|
|
|
中间体2
|
5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid
|
163521-19-5
|
维拉佐酮羧基酸
|
|
托比司他
|
托比司他
|
2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-
|
577778-58-6
|
|
|
中间体1
|
4-Pyridinecarboxylicacid,2-cyano-,hydrazide
|
135048-32-7
|
2-氰基异烟酰肼
|
|
罗氟司特
|
罗氟司特
|
Roflumilast
|
162401-32-3
|
3-(环丙基甲氧基)-N-(3,5-二氯吡啶-4-基)-4-(二氟甲氧基)苯甲酰胺
|
|
盐酸氯卡色林
|
盐酸氯卡色林
|
Lorcaserin hydrochloride
|
846589-98-8
|
(R)-8-氯-1-甲基-2,3,4,5-四氢-1H-3-苯并氮杂卓盐酸盐
|
|
盐酸氯卡色林中间体1
|
1-((4-chlorophenethyl)amino)propan-2-ol
|
847063-13-2
|
1-[2-(4-氯-苯基)-乙基氨基]-2-丙醇
|
|
盐酸氯卡色林中间体2
|
2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride
|
953789-37-2
|
1-[[2-(4-氯苯基)乙基]氨基]-2-氯丙烷盐酸盐
|
|
盐酸氯卡色林中间体3
|
8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
|
616201-80-0
|
8-氯-1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂卓
|
|
盐酸氯卡色林中间体4
|
(R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine (2R,3R)-2,3-dihydroxysuccinate
|
847063-12-1
|
8-氯-1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂卓半酒石酸盐
|
|
奥贝胆酸
|
6-乙基鹅去氧胆酸
|
6-Ethylchenodeoxycholic acid
|
459789-99-2
|
6-乙基鹅去氧胆酸
|
|
中间体1
|
(E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid methyl ester
|
863239-59-2
|
E/Z）-3α羟基-6-亚乙基-7-酮-5β-胆烷酸-24-甲酯
|
|
中间体2
|
3α-hydroxy-6-ethyl-7-keto-5β-cholan-24-oic acid
|
915038-26-5
|
3α-羟基-6-乙基-7-酮-5β-胆-24-酸
|
|
哌啶甲酸
|
|
S-2—Pipecolinic Acid
|
3105-95-1
|
S-2-哌啶甲酸
|
|
帕布西利布
|
帕布西利布
|
Palbociclib isethionate
|
827022-33-3
|
帕布西利布羟基乙磺酸盐
|
|
帕布西利布中间体1
|
4-[6-[(6-Bromo-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
|
571188-82-4
|
4-[6-[(6-溴-8-环戊基-7,8-二氢-5-甲基-7-氧代吡啶并[2,3-d]嘧啶-2-基)氨基]-3-吡啶基]-1-哌嗪羧酸叔丁酯
|
|
帕布西利布中间体2
|
tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate (CAS No.866084-31-3)
|
866084-31-3
|
2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3-D]嘧啶-2-基]氨基} -3-吡啶基)-1-哌嗪甲酸
|
|
帕布西利布中间体3
|
6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one
|
571190-30-2
|
6-乙酰基-8-环戊基-5-甲基-2-[[5-(哌嗪-1-基)吡啶-2-基]氨基]-8H-吡啶并[2,3-D]嘧啶-7-酮
|
|
枸橼酸铁
|
枸橼酸铁
|
Ferric Citrate
|
3522-50-7
|
枸橼酸铁
|
|
甲苯磺酸依度沙班
|
甲苯磺酸依度沙班
|
Edoxaban TsOH salt
|
480449-71-6
|
依度沙班对甲苯磺酸盐
|
|
甲苯磺酸依度沙班
中间体1
|
tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate
|
480452-36-6
|
[(1R,2S,5S)-2-[[2-[(5-氯吡啶-2-基)氨基]-2-氧代乙酰基]氨基]-5-(二甲基氨基羰基)环己基]氨基甲酸叔丁酯
|
|
甲苯磺酸依度沙班
中间体2
|
N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide
|
480449-70-5
|
N-(5-氯-2-吡啶基)-N'-[(1S,2R,4S)-4-[(二甲基氨基)乙酰基]-2-[[(4,5,6,7-四氢-5-甲基噻唑并[5,4-c]吡啶-2-基)甲酰]氨基]环己基]乙二酰胺
|
|
磷酸特地唑胺
|
磷酸特地唑胺
|
TEDIZOLID PHOSPHATE；-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate
|
856867-55-5
|
(R)-3-(4-(2-(2-甲基四唑-5-基)吡啶-5-基)-3-氟苯基)-5-羟甲基噁唑烷-2-酮磷酸酯
|
|
磷酸特地唑胺
中间体1
|
3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
|
856866-72-3
|
3-[3-氟-4-[6-(2-甲基-2H-四唑-5-基)-3-吡啶基]苯基]-5-(羟基甲基)-2-恶唑烷酮
|
|
阿普斯特
|
阿普斯特
|
Apremilast；(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
|
608141-41-9
|
(S)-2-[1-(3-乙氧基-4-甲氧基苯基)-2-甲磺酰基乙基]-4-乙酰基氨基异吲哚啉-1,3-二酮
|
|
阿普斯特
中间体1
|
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt
|
608141-43-1
|
(S)-1-(3-乙氧基-4-甲氧基苯基)-2-(甲基磺酰基)乙胺 N-乙酰基-L-亮氨酸盐
|
|
枸橼酸托法替布
|
枸橼酸托法替布
|
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
|
540737-29-9
|
3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-d]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙腈，枸橼酸盐（1：1）;
|
|
枸橼酸托法替布
中间体一
|
7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]-
|
923036-30-0
|
N-甲基-N-((3R,4R)-4-甲基-1-苄基-3-哌啶基)-7H-吡咯并[2,3-D]嘧啶-4-胺
|
|
枸橼酸托法替布
中间体二
|
N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
|
477600-73-0
|
N-((3R,4R)-1-苄基-4-甲基哌啶-3-基)-N-甲基-7H-吡咯[2,3-d]嘧啶-4-胺
|
|
枸橼酸托法替布
中间体三
|
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
|
477600-74-1
|
N-甲基-N-((3R,4R)-4-甲基哌啶-3-基)-7H-吡咯并[2,3-D]嘧啶-4-胺
|
|
枸橼酸托法替布
中间体四
|
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
|
477600-75-2
|
3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯[2,3-d]嘧啶-4-基)胺基)哌啶-1-基)-3-氧代丙腈
|
|
甲磺酸伊马替尼
|
甲磺酸伊马替尼
|
N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide methanesulfonate
|
220127-57-1
|
4-[(4-甲基-1-哌嗪基)甲基]-N-[4-甲基-3-[4-(3-吡啶基)-2-嘧啶基]氨基]苯基]苯甲酰胺甲磺酸盐
|
|
中间体1（即伊马替尼游离碱）
|
N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
|
152459-95-5
|
4-[(4-甲基-1-哌嗪基)甲基]-N-[4-甲基-3-[4-(3-吡啶基)-2-嘧啶基]氨基]苯基]苯甲酰胺
|
|
福沙匹坦
|
福沙匹坦
|
D-Glucitol, 1-deoxy-1-(methylamino)-, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4- morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phosphonate (2:1)
|
265121-04-8
|
1-脱氧-1-(甲基氨基)-D-葡萄糖醇 [3-[[(2R,3S)-2-[(1R)-1-[3,5-双(三氟甲基)苯基]乙氧基]-3-(4-氟苯基)-4-吗啉基]甲基]-2,5-二氢-5-氧代-1H-1,2,4-三唑-1-基]膦酸盐
|
|
中间体1（即阿瑞匹坦）
|
5-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2h-1,2,4-triazol-3-one
|
170729-80-3
|
5-[2(R)-[1(R)-[3,5-二(三氟甲基)苯基]乙氧基]-3(S)-(4-氟苯基)吗啉-4-基甲基]-3,4-二氢-2H-1,2,4-三唑-3-酮
|
|
中间体2（福沙匹坦单卞酯）
|
benzyl hydrogen (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate
|
889852-02-2
|
3-[[(2R,3S)-2-[(1R)-1-[3,5-二(三氟甲基)苯基]乙氧基] -3-(4-氟苯基)-4-吗啉基]甲基] -2，5-二氢-5-氧代-1H-1,2,4-三氮唑-1-基]膦酸单苄酯
|
|
盐酸他喷他多
|
盐酸他喷他多
|
3-((2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl)phenol hydrochloride
|
175591-09-0
|
(-)-(1R,2R)-3-(3-二甲氨基-1-乙基-2-甲基丙基)苯酚盐酸盐
|
|
中间体1
|
3-(1-dimethylamino-2-methyl-pentan-3-yl)phenol
|
175591-23-8
|
3-((1R,2R)-3-(二甲基氨基)-1-乙基-2-甲基丙基)苯酚
|